FUCA2

Across TCGA patient cohorts, FUCA2 protein abundance is significantly associated with the RNA expression of many other genes, with 9,838 significant associations in total. GBM shows the largest number of these associations.

The most reproducible FUCA2-associated genes across cancer lineages are AGR2, XBP1, and ARFGEF3. Each is linked with FUCA2 in more than 4 cancer types. Because this analysis shows association rather than direction, both FUCA2-to-partner and partner-to-FUCA2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FUCA2 versus AGR2 in BRCA, with a Pearson correlation of 0.37.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FUCA2→partner) and Y-score (partner→FUCA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	AGR2 →	+3.085	+0.479	<.001	<.001	3	5
BRCA	XBP1 →	+1.200	+0.436	<.001	<.001	3	4
HNSC	ARFGEF3 →	+1.137	+0.216	<.001	.003	3	4
LSCC	TSPAN1 →	+1.950	+0.418	<.001	<.001	3	4
BRCA	GDF15 →	+1.443	+0.453	<.001	<.001	3	4
UCEC	TTC6 →	+1.867	+0.402	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,838 associations by consensus.

FUCA2 vs AGR2 — BRCA

Explore this scatter interactively →