FTSJ3

Across TCGA patient cohorts, FTSJ3 mutation is significantly associated with the RNA expression of many other genes, with 2,430 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FTSJ3-associated genes across cancer lineages are SFXN1, NUDCD2, and TYMSOS. Each is linked with FTSJ3 in more than 2 cancer types. Because this analysis shows association rather than direction, both FTSJ3-to-partner and partner-to-FTSJ3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SFXN1 grouped by FTSJ3-low versus FTSJ3-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FTSJ3→partner) and Y-score (partner→FTSJ3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SFXN1 →	+0.514	+2.243	<.001	.001	3	3
UCEC	NUDCD2 →	+0.417	+2.021	.003	.001	3	3
COAD	TYMSOS →	+0.819	+3.459	.002	.005	3	3
COAD	TOMM22 →	+0.506	+3.472	<.001	.002	3	3
UCEC	CENPM →	+0.516	+2.392	.006	<.001	3	3
UCEC	BAG1 →	+0.433	+2.000	.001	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,430 associations by consensus.

SFXN1 by FTSJ3 expression — UCEC

Explore this box plot interactively →