FTSJ3

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, FTSJ3 mutation is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible FTSJ3-associated genes across cancer lineages are OR2M4, GPR148, and OR4C6. Each is linked with FTSJ3 in more than 1 cancer types. Because this analysis shows association rather than direction, both FTSJ3-to-partner and partner-to-FTSJ3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR2M4 grouped by FTSJ3-low versus FTSJ3-high in OVARY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FTSJ3→partner) and Y-score (partner→FTSJ3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVARYOR2M4 →+0.055+3.700.001.00531
OVARYGPR148 →+0.056+4.095<.001.00331
OVARYOR4C6 →+0.087+3.791.003.00731
OVARYRAD51AP2 →+0.078+3.963<.001.00431
BLOOD_LeukemiaMS4A5 →+0.049+4.384<.001.00631
BLOOD_LeukemiaDPRX →+0.073+4.060<.001.00331
Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

OR2M4 by FTSJ3 expression — OVARY

Box plot of OR2M4 in FTSJ3-low vs FTSJ3-high samples in OVARY.

Explore this box plot interactively →

Exploration