FTH1P27

Across TCGA pan-cancer cohorts, FTH1P27 RNA is linked to patient survival in 12 of 34 cancer types, making it the most broadly survival-associated FTH1P27 data layer.

The strongest signal is observed in mesothelioma (MESO), where higher FTH1P27 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated FTH1P27 expression acts as an unfavorable survival marker, although some lineages such as READ show a favorable association.

MESO, LUSC, and BRCA are the cancer types where FTH1P27 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
MESO	OS	Tertile	All	0.239	0.453	<.001	81	view →
LUSC	DFS	Tertile	All	0.181	0.406	.001	66	view →
BRCA	OS	Tertile	III,IV	0.616	0.851	.001	63	view →
THCA	DFS	Tertile	II,III,IV	0.846	0.953	<.001	30	view →
THYM	OS	Tertile	All	0.791	0.979	.025	21	view →
LUAD	DFS	Tertile	IV	0.333	0.671	.048	18	view →
ESCA	OS	Quartile	II,III,IV	0.169	1.000	<.001	15	view →
LAML	DFS	Tertile	All	0.391	0.589	.046	12	view →
READ	OS	Tertile	All	0.860	0.640	.039	10	view →
PCPG	DFS	Tertile	All	0.437	0.855	.008	9	view →
ACC	OS	Tertile	IV	0.353	0.751	.028	9	view →
LGG	OS	Tertile	All	0.810	0.906	.022	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 12 lineages.

FTH1P27–MESO (OS)

Open the MESO breakdown →