FTH1P27

Across TCGA pan-cancer cohorts, FTH1P27 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of FTH1P27’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where FTH1P27 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types FTH1P27 is over-expressed in tumor, although a few such as KICH show the opposite, repressed pattern.

HNSC, STAD, and THCA are the cancer types where FTH1P27 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in FTH1P27 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	All	III,IV	+0.046	.003	8	view →
STAD	Female	All	+0.124	.020	4	view →
THCA	Female	All	+0.049	<.001	4	view →
COAD	Female	All	+0.148	.011	3	view →
KICH	All	II,III,IV	−0.119	.024	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

FTH1P27–HNSC

Open the HNSC breakdown →