FSTL3

Across TCGA cell cohorts, FSTL3 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible FSTL3-associated genes across cancer lineages are WFDC8, TRIM60, and TPRX1. Each is linked with FSTL3 in more than 1 cancer types. Because this analysis shows association rather than direction, both FSTL3-to-partner and partner-to-FSTL3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, WFDC8 grouped by FSTL3-low versus FSTL3-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FSTL3→partner) and Y-score (partner→FSTL3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	WFDC8 →	+0.011	+4.867	.009	.009	3	1
BLOOD_Lymphoma	TRIM60 →	+0.352	+4.867	<.001	.009	3	1
BLOOD_Lymphoma	TPRX1 →	+0.006	+5.209	<.001	.005	3	1
BLOOD_Lymphoma	C1orf232 →	+0.042	+5.643	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

WFDC8 by FSTL3 expression — BLOOD_Lymphoma

Explore this box plot interactively →