FSIP2-AS1

Across TCGA pan-cancer cohorts, FSIP2-AS1 RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated FSIP2-AS1 data layer.

The strongest signal is observed in uveal melanoma (UVM), where higher FSIP2-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated FSIP2-AS1 expression acts as an unfavorable survival marker, although some lineages such as BLCA and BRCA show a favorable association.

UVM, BLCA, and LGG are the cancer types where FSIP2-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UVM	DFS	Median	III,IV	0.259	0.714	.003	51	view →
BLCA	DFS	Median	All	0.573	0.449	.001	42	view →
LGG	DFS	Median	All	0.666	0.805	<.001	33	view →
KIRC	DFS	Tertile	All	0.433	0.699	<.001	31	view →
BRCA	OS	Tertile	III,IV	0.892	0.742	.003	19	view →
LUSC	OS	Tertile	All	0.806	0.708	.007	18	view →
SKCM	OS	Median	All	0.394	0.251	.005	12	view →
LIHC	DFS	Quartile	All	0.194	0.309	.023	11	view →
PAAD	DFS	Median	All	0.447	0.248	.006	9	view →
THYM	DFS	Tertile	All	1.000	0.721	.023	7	view →
ESCA	DFS	Median	III,IV	0.299	0.505	.018	6	view →
LUAD	DFS	Median	IV	0.325	0.595	.026	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

FSIP2-AS1–UVM (DFS)

Open the UVM breakdown →