FSIP1

Across TCGA patient cohorts, FSIP1 mutation is significantly associated with the RNA expression of many other genes, with 2,537 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FSIP1-associated genes across cancer lineages are RNU1-17P, RNU6-1214P, and RPL9P13. Each is linked with FSIP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both FSIP1-to-partner and partner-to-FSIP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU1-17P grouped by FSIP1-low versus FSIP1-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FSIP1→partner) and Y-score (partner→FSIP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	RNU1-17P →	+0.445	+5.103	<.001	.008	3	2
CESC	RNU6-1214P →	+0.446	+5.306	<.001	.006	3	2
CESC	RPL9P13 →	+0.137	+5.010	<.001	.009	3	2
UCEC	CCT5 →	+0.530	+3.054	.001	<.001	3	2
UCEC	NMRAL1 →	+0.358	+3.763	.001	<.001	3	2
UCEC	CCT8 →	+0.390	+2.177	.003	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,537 associations by consensus.

RNU1-17P by FSIP1 expression — CESC

Explore this box plot interactively →