FSIP1

Across TCGA pan-cancer cohorts, FSIP1 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated FSIP1 data layer compared with 3 for mutation status.

The strongest signal is observed in breast invasive carcinoma (BRCA), where higher FSIP1 RNA is associated with better overall survival. In most high-consensus cancer types, elevated FSIP1 expression acts as an unfavorable survival marker, although some lineages such as BRCA and SKCM show a favorable association.

BRCA, LGG, and MESO are the cancer types where FSIP1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BRCA	OS	Median	All	0.952	0.896	<.001	65	view →
LGG	OS	Median	All	0.747	0.873	<.001	43	view →
MESO	OS	Tertile	All	0.380	0.700	.003	38	view →
KIRP	DFS	Median	IV	0.039	0.524	.002	34	view →
SKCM	OS	Median	All	0.456	0.296	.001	28	view →
KICH	DFS	Quartile	II,III,IV	0.588	1.000	.007	24	view →
LIHC	OS	Median	All	0.616	0.780	.001	24	view →
UVM	OS	Quartile	All	0.424	0.853	.005	18	view →
HNSC	OS	Quartile	All	0.536	0.820	.006	13	view →
SCLC	DFS	Median	IV	0.137	0.559	.008	12	view →
LUAD	OS	Quartile	III,IV	0.502	0.822	.021	11	view →
THCA	DFS	Median	All	0.962	0.905	.005	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

FSIP1–BRCA (OS)

Open the BRCA breakdown →