FSIP1

Across TCGA cell cohorts, FSIP1 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible FSIP1-associated genes across cancer lineages are PATE4, MBD3L2, and GNAT1. Each is linked with FSIP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both FSIP1-to-partner and partner-to-FSIP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PATE4 grouped by FSIP1-low versus FSIP1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FSIP1→partner) and Y-score (partner→FSIP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	PATE4 →	+0.054	+4.095	<.001	.009	3	1
LUNG_NSCLC_LUAD	MBD3L2 →	+0.130	+5.228	<.001	.005	3	1
BLOOD_Leukemia	GNAT1 →	+0.063	+3.855	<.001	.007	3	1
BLOOD_Leukemia	IFNL2 →	+0.043	+4.060	<.001	.003	3	1
BLOOD_Leukemia	FAM90A26 →	+0.010	+4.824	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

PATE4 by FSIP1 expression — LARGE_INTESTINE

Explore this box plot interactively →