Across TCGA patient cohorts, FSD2 mutation is significantly associated with the RNA expression of many other genes, with 3,454 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FSD2-associated genes across cancer lineages are RNU6-342P, CSH2, and RNU2-51P. Each is linked with FSD2 in more than 2 cancer types. Because this analysis shows association rather than direction, both FSD2-to-partner and partner-to-FSD2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FSD2→partner) and Y-score (partner→FSD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RNU6-342P →	+0.177	+2.227	<.001	.008	3	3
COAD	CSH2 →	+0.184	+3.797	<.001	.003	3	3
UCEC	RNU2-51P →	+0.269	+1.374	<.001	.004	3	3
UCEC	RNU6-548P →	+0.395	+1.306	.002	.005	3	3
READ	SNX18P12 →	+0.143	+4.023	.004	.005	3	2
SKCM	ATP5PD →	+0.312	+2.228	.007	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,454 associations by consensus.

Exploration

FSD2 survival (RNA) · tumor vs normal (RNA) · all FSD2 data types