FSD1L

Across TCGA patient cohorts, FSD1L mutation is significantly associated with the RNA expression of many other genes, with 2,483 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FSD1L-associated genes across cancer lineages are TRAJ12, SNORD114-18, and RNU6-74P. Each is linked with FSD1L in more than 2 cancer types. Because this analysis shows association rather than direction, both FSD1L-to-partner and partner-to-FSD1L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TRAJ12 grouped by FSD1L-low versus FSD1L-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FSD1L→partner) and Y-score (partner→FSD1L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	TRAJ12 →	+0.599	+4.193	.002	.009	3	3
UCEC	SNORD114-18 →	+0.406	+2.977	<.001	<.001	3	2
UCEC	RNU6-74P →	+0.138	+2.397	.007	.009	3	2
UCEC	RPL22P14 →	+0.087	+2.203	<.001	.004	3	2
COAD	RN7SL83P →	+0.516	+5.392	<.001	.002	3	2
UCEC	RNA5SP418 →	+0.695	+2.162	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,483 associations by consensus.

TRAJ12 by FSD1L expression — CESC

Explore this box plot interactively →