FSD1L

Across TCGA pan-cancer cohorts, FSD1L RNA is linked to patient survival in 28 of 34 cancer types, making it the most broadly survival-associated FSD1L data layer compared with 3 for mutation status and 6 for mass-spec protein.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where higher FSD1L RNA is associated with worse overall survival. In most high-consensus cancer types, elevated FSD1L expression acts as an unfavorable survival marker, although some lineages such as THYM and KIRC show a favorable association.

LIHC, THYM, and BLCA are the cancer types where FSD1L RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LIHC	OS	Median	All	0.606	0.763	<.001	85	view →
THYM	DFS	Quartile	All	0.902	0.577	<.001	54	view →
BLCA	DFS	Tertile	All	0.264	0.639	.001	54	view →
CESC	OS	Tertile	III,IV	0.544	0.905	.003	52	view →
ACC	DFS	Quartile	All	0.291	0.792	.001	41	view →
KIRC	DFS	Median	II,III,IV	0.611	0.338	.004	40	view →
LUSC	DFS	Tertile	III,IV	0.120	0.877	.002	36	view →
LGG	DFS	Tertile	All	0.522	0.284	<.001	35	view →
UCS	DFS	Tertile	IV	0.942	0.403	.024	24	view →
MESO	OS	Median	All	0.467	0.615	.011	22	view →
PAAD	DFS	Median	All	0.478	0.257	.004	18	view →
READ	OS	Quartile	II,III,IV	1.000	0.331	.005	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 28 lineages.

FSD1L–LIHC (OS)

Open the LIHC breakdown →