FSD1L

mutation — cross-omics
Cross-omicsMUTATION → MUTATIONCell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, FSD1L mutation is significantly associated with the mutation status of many other genes, with 622 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FSD1L-associated genes across cancer lineages are GRIN2D, BAIAP2, and IPO7. Each is linked with FSD1L in more than 2 cancer types. Because this analysis shows association rather than direction, both FSD1L-to-partner and partner-to-FSD1L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GRIN2D grouped by FSD1L-low versus FSD1L-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FSD1L→partner) and Y-score (partner→FSD1L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINEGRIN2D →+2.865+4.217.007.00713
UPPER_AERODIGESTIVE_TRACTBAIAP2 →+4.954+4.392.008.00813
UPPER_AERODIGESTIVE_TRACTIPO7 →+4.954+4.392.008.00813
LARGE_INTESTINEBRCA1 →+2.865+4.217.007.00712
LARGE_INTESTINESLC13A2 →+3.087+4.392.005.00512
UPPER_AERODIGESTIVE_TRACTTCF20 →+4.954+4.392.008.00812
Each partner links to its Q-omics profile. Showing the 6 strongest of 622 associations by consensus.

GRIN2D by FSD1L expression — LARGE_INTESTINE

Box plot of GRIN2D in FSD1L-low vs FSD1L-high samples in LARGE_INTESTINE.

Explore this box plot interactively →

Exploration