FSCN3

Across TCGA cell cohorts, FSCN3 mutation is significantly associated with the RNA expression of many other genes, with 504 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FSCN3-associated genes across cancer lineages are TAS1R2, OR52L1, and TMEM212. Each is linked with FSCN3 in more than 1 cancer types. Because this analysis shows association rather than direction, both FSCN3-to-partner and partner-to-FSCN3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TAS1R2 grouped by FSCN3-low versus FSCN3-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FSCN3→partner) and Y-score (partner→FSCN3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	TAS1R2 →	+0.007	+3.604	<.001	.004	3	2
BLOOD_Leukemia	OR52L1 →	+0.045	+5.201	<.001	.006	3	1
LUNG_SCLC	TMEM212 →	+0.648	+4.044	<.001	.009	3	1
LUNG_NSCLC_LUAD	COX4I2 →	+0.059	+4.228	<.001	<.001	3	1
LUNG_NSCLC_LUAD	IL1F10 →	+0.148	+3.989	.001	.002	3	1
BREAST	POTEB →	+0.026	+5.169	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 504 associations by consensus.

TAS1R2 by FSCN3 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →