FSBP

Across TCGA patient cohorts, FSBP protein abundance is significantly associated with the RNA expression of many other genes, with 2,066 significant associations in total. GBM shows the largest number of these associations.

The most reproducible FSBP-associated genes across cancer lineages are NCKAP1L, WDFY4, and BPHL. Each is linked with FSBP in more than 1 cancer types. Because this analysis shows association rather than direction, both FSBP-to-partner and partner-to-FSBP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FSBP versus NCKAP1L in BRCA, with a Pearson correlation of -0.68.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FSBP→partner) and Y-score (partner→FSBP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	NCKAP1L →	-1.101	-0.699	<.001	.007	3	2
GBM	WDFY4 →	-0.864	-0.521	.002	<.001	3	2
BRCA	BPHL →	+0.667	+0.483	<.001	.008	3	2
BRCA	IRF8 →	-1.094	-0.684	.006	.008	3	2
BRCA	P2RY8 →	-1.305	-0.905	<.001	.001	3	2
BRCA	RILPL1 →	+0.505	+0.498	.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,066 associations by consensus.

FSBP vs NCKAP1L — BRCA

Explore this scatter interactively →