FSBP

Across TCGA pan-cancer cohorts, FSBP RNA is linked to patient survival in 16 of 34 cancer types, making it the most broadly survival-associated FSBP data layer compared with 1 for mutation status and 4 for mass-spec protein.

The strongest signal is observed in rectum adenocarcinoma (READ), where higher FSBP RNA is associated with worse overall survival. In most high-consensus cancer types, elevated FSBP expression acts as an unfavorable survival marker, although some lineages such as CHOL and ESCA show a favorable association.

READ, LGG, and UCEC are the cancer types where FSBP RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
READ	OS	Tertile	All	0.242	0.841	<.001	60	view →
LGG	OS	Median	All	0.731	0.885	<.001	37	view →
UCEC	OS	Tertile	IV	0.336	0.764	.003	36	view →
KIRP	OS	Tertile	All	0.864	0.962	.007	30	view →
PAAD	OS	Tertile	II,III,IV	0.355	0.588	.002	27	view →
CHOL	DFS	Tertile	All	1.000	0.219	.007	27	view →
CESC	DFS	Tertile	IV	0.053	0.529	<.001	18	view →
LUAD	DFS	Tertile	IV	0.430	0.750	.018	18	view →
TGCT	OS	Quartile	All	0.828	0.989	.002	10	view →
COAD	DFS	Tertile	III,IV	0.109	0.415	.036	9	view →
MESO	OS	Tertile	III,IV	0.153	0.590	.010	9	view →
SARC	DFS	Tertile	All	0.296	0.508	.034	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 16 lineages.

FSBP–READ (OS)

Open the READ breakdown →