FRZB

Across TCGA patient cohorts, FRZB protein abundance is significantly associated with the RNA expression of many other genes, with 14,224 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible FRZB-associated genes across cancer lineages are COL14A1, SFRP4, and MGP. Each is linked with FRZB in more than 8 cancer types. Because this analysis shows association rather than direction, both FRZB-to-partner and partner-to-FRZB results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FRZB versus COL14A1 in BRCA, with a Pearson correlation of 0.64.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FRZB→partner) and Y-score (partner→FRZB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	COL14A1 →	+1.774	+0.957	<.001	<.001	3	9
UCEC	SFRP4 →	+2.437	+0.733	<.001	<.001	3	8
BRCA	MGP →	+2.039	+0.699	.001	.002	3	8
OV	C7 →	+2.475	+0.806	<.001	.003	3	8
CCRCC	PTGIS →	+1.407	+0.924	<.001	<.001	3	8
CCRCC	FBLN5 →	+1.325	+0.724	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,224 associations by consensus.

FRZB vs COL14A1 — BRCA

Explore this scatter interactively →