FRY-AS1

Across TCGA pan-cancer cohorts, FRY-AS1 RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated FRY-AS1 data layer.

The strongest signal is observed in pancreatic adenocarcinoma (PAAD), where higher FRY-AS1 RNA is associated with better overall survival. In most high-consensus cancer types, elevated FRY-AS1 expression acts as an unfavorable survival marker, although some lineages such as PAAD and LGG show a favorable association.

PAAD, UVM, and LGG are the cancer types where FRY-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PAAD	OS	Tertile	All	0.598	0.278	<.001	82	view →
UVM	OS	Tertile	III,IV	0.231	0.836	.001	33	view →
LGG	OS	Tertile	All	0.663	0.430	.001	27	view →
KIRC	DFS	Tertile	II,III,IV	0.461	0.655	.018	26	view →
THYM	DFS	Quartile	All	0.568	0.967	.001	25	view →
GBM	OS	Quartile	All	0.527	0.320	.005	24	view →
UCS	DFS	Median	II,III,IV	0.539	0.249	.025	24	view →
BLCA	DFS	Tertile	IV	0.654	0.249	.001	23	view →
KIRP	DFS	Tertile	All	1.000	0.662	.011	18	view →
CHOL	OS	Median	All	0.136	0.876	<.001	18	view →
DLBC	DFS	Quartile	All	1.000	0.402	.022	15	view →
KICH	DFS	Median	III,IV	0.369	0.895	.005	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

FRY-AS1–PAAD (OS)

Open the PAAD breakdown →