FRS3

Across TCGA patient cohorts, FRS3 protein abundance is significantly associated with the RNA expression of many other genes, with 4,813 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible FRS3-associated genes across cancer lineages are STS, ECH1, and TUBB4A. Each is linked with FRS3 in more than 1 cancer types. Because this analysis shows association rather than direction, both FRS3-to-partner and partner-to-FRS3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FRS3 versus STS in GBM, with a Pearson correlation of 0.29.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FRS3→partner) and Y-score (partner→FRS3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	STS →	+0.439	+0.517	.002	.002	3	1
GBM	ECH1 →	+0.209	+0.449	.005	.003	3	1
GBM	TUBB4A →	+1.822	+0.525	.001	.001	3	1
GBM	PLD3 →	+0.413	+0.505	<.001	.001	3	1
GBM	APLP1 →	+1.216	+0.622	<.001	<.001	3	1
GBM	RAB3A →	+1.406	+0.691	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,813 associations by consensus.

FRS3 vs STS — GBM

Explore this scatter interactively →