FRMPD3

Across TCGA patient cohorts, FRMPD3 mutation is significantly associated with the RNA expression of many other genes, with 4,891 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FRMPD3-associated genes across cancer lineages are PSMD9, MRM3, and PTTG1. Each is linked with FRMPD3 in more than 3 cancer types. Because this analysis shows association rather than direction, both FRMPD3-to-partner and partner-to-FRMPD3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PSMD9 grouped by FRMPD3-low versus FRMPD3-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FRMPD3→partner) and Y-score (partner→FRMPD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PSMD9 →	+0.363	+1.743	<.001	<.001	3	4
COAD	MRM3 →	+0.467	+2.937	<.001	<.001	3	4
UCEC	PTTG1 →	+0.561	+1.691	<.001	<.001	3	4
SKCM	C19orf48 →	+0.384	+2.372	.005	.002	3	4
UCEC	CDC45 →	+0.633	+1.894	<.001	<.001	3	4
UCEC	RANBP1 →	+0.501	+1.415	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,891 associations by consensus.

PSMD9 by FRMPD3 expression — UCEC

Explore this box plot interactively →