FRMPD3

Across TCGA patient cohorts, FRMPD3 mutation is significantly associated with the total protein of many other genes, with 70 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FRMPD3-associated genes across cancer lineages are Stathmin, ATM, and Caspase-7-cleavedD198. Each is linked with FRMPD3 in more than 4 cancer types. Because this analysis shows association rather than direction, both FRMPD3-to-partner and partner-to-FRMPD3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Stathmin grouped by FRMPD3-low versus FRMPD3-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FRMPD3→partner) and Y-score (partner→FRMPD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Stathmin →	+0.114	+1.237	.001	.004	3	5
UCEC	ATM →	-0.549	-1.544	<.001	<.001	3	3
COAD	Caspase-7-cleavedD198 →	+0.803	+1.915	.005	.009	3	3
UCEC	eEF2 →	+0.216	+1.584	.022	.032	3	3
UCEC	eIF4E →	+0.180	+2.261	.001	<.001	3	3
UCEC	FASN →	+0.312	+1.237	.002	.004	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 70 associations by consensus.

Stathmin by FRMPD3 expression — UCEC

Explore this box plot interactively →