FRMPD3

Across TCGA cell cohorts, FRMPD3 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,621 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible FRMPD3-associated GO terms across cancer lineages are Regulation of syncytium formation by plasma membrane fusion, Regulation of transcription initiation by RNA polymerase II, and Stress granule assembly. Each is linked with FRMPD3 in more than 8 cancer types. Because this analysis shows association rather than direction, both FRMPD3-to-partner and partner-to-FRMPD3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of syncytium formation by plasma membrane fusion grouped by FRMPD3-low versus FRMPD3-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FRMPD3→partner) and Y-score (partner→FRMPD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Regulation of syncytium formation by plasma membrane fusion →	+0.095	+0.241	<.001	<.001	3	9
UPPER_AERODIGESTIVE_TRACT	Regulation of transcription initiation by RNA polymerase II →	+0.069	+0.245	<.001	<.001	3	9
UPPER_AERODIGESTIVE_TRACT	Stress granule assembly →	+0.115	+0.164	.002	.005	3	8
STOMACH	Spliceosomal complex assembly →	+0.099	+0.318	<.001	.005	3	8
UPPER_AERODIGESTIVE_TRACT	Regulation of myoblast fusion →	+0.087	+0.154	<.001	.004	3	8
UPPER_AERODIGESTIVE_TRACT	Negative regulation of myoblast fusion →	+0.117	+0.223	<.001	.005	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,621 associations by consensus.

Regulation of syncytium formation by plasma membrane fusion by FRMPD3 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →