FRMPD2B

Across TCGA patient cohorts, FRMPD2B mutation is significantly associated with the RNA expression of many other genes, with 1,326 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FRMPD2B-associated genes across cancer lineages are KXD1, FEM1A, and TTTY12. Each is linked with FRMPD2B in more than 1 cancer types. Because this analysis shows association rather than direction, both FRMPD2B-to-partner and partner-to-FRMPD2B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KXD1 grouped by FRMPD2B-low versus FRMPD2B-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FRMPD2B→partner) and Y-score (partner→FRMPD2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	KXD1 →	+0.460	+3.343	<.001	.005	3	2
UCEC	FEM1A →	+0.396	+3.491	<.001	.002	3	2
LUAD	TTTY12 →	+0.065	+5.481	<.001	.005	3	2
LUAD	CA15P2 →	+0.049	+5.481	<.001	.005	3	2
SKCM	FABP12 →	+0.082	+2.181	.001	.008	3	2
UCEC	RNU6-271P →	+0.263	+3.152	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,326 associations by consensus.

KXD1 by FRMPD2B expression — UCEC

Explore this box plot interactively →