FRMPD2B

Across TCGA pan-cancer cohorts, FRMPD2B RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated FRMPD2B data layer compared with 3 for mutation status.

The strongest signal is observed in lymphoid neoplasm diffuse large b-cell lymphoma (DLBC), where higher FRMPD2B RNA is associated with worse overall survival. In most high-consensus cancer types, elevated FRMPD2B expression acts as an unfavorable survival marker, although some lineages such as BLCA and UCEC show a favorable association.

DLBC, BLCA, and UCEC are the cancer types where FRMPD2B RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
DLBC	OS	Median	All	0.650	1.000	<.001	140	view →
BLCA	OS	Median	All	0.544	0.351	.001	93	view →
UCEC	OS	Tertile	All	0.770	0.566	.001	36	view →
KIRC	OS	Median	All	0.912	0.834	<.001	34	view →
TGCT	DFS	Quartile	II,III,IV	0.729	0.996	.034	30	view →
LUAD	OS	Tertile	All	0.476	0.280	.001	27	view →
LGG	OS	Median	All	0.928	0.849	.003	22	view →
THYM	DFS	Tertile	III,IV	0.214	1.000	.008	19	view →
PAAD	DFS	Tertile	III,IV	0.118	0.734	.014	18	view →
ACC	OS	Median	IV	0.277	0.721	.015	15	view →
OV	OS	Median	II,III,IV	0.870	0.824	.025	14	view →
COAD	OS	Tertile	All	0.934	0.615	.023	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 19 lineages.

FRMPD2B–DLBC (OS)

Open the DLBC breakdown →