FRMD6-AS1

Across TCGA pan-cancer cohorts, FRMD6-AS1 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated FRMD6-AS1 data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher FRMD6-AS1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated FRMD6-AS1 expression acts as an unfavorable survival marker, although some lineages such as BRCA and LAML show a favorable association.

ACC, BRCA, and LIHC are the cancer types where FRMD6-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	OS	Median	All	0.309	0.779	<.001	82	view →
BRCA	DFS	Tertile	III,IV	0.946	0.803	.001	50	view →
LIHC	DFS	Tertile	All	0.441	0.606	.001	49	view →
LAML	DFS	Tertile	All	0.620	0.341	<.001	44	view →
KICH	OS	Median	III,IV	0.556	1.000	.010	42	view →
UCS	DFS	Median	IV	0.909	0.416	.008	34	view →
SKCM	DFS	Median	II,III,IV	0.473	0.690	.002	31	view →
COAD	DFS	Median	II,III,IV	0.386	0.666	.019	17	view →
LUAD	DFS	Tertile	All	0.236	0.424	.013	17	view →
UVM	DFS	Median	All	0.734	0.488	.008	16	view →
MESO	DFS	Median	II,III,IV	0.303	0.597	.013	15	view →
LUSC	OS	Median	All	0.823	0.701	.007	14	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

FRMD6-AS1–ACC (OS)

Open the ACC breakdown →