FRMD4B

Across TCGA patient cohorts, FRMD4B RNA expression is significantly associated with the protein abundance of many other proteins, with 17,410 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible FRMD4B-associated proteins across cancer lineages are TOP1, PPM1F, and PDCD6IP. Each is linked with FRMD4B in more than 5 cancer types. Because this analysis shows association rather than direction, both FRMD4B-to-partner and partner-to-FRMD4B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FRMD4B versus TOP1 in LUAD, with a Pearson correlation of -0.42.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FRMD4B→partner) and Y-score (partner→FRMD4B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	TOP1 →	-0.462	-0.718	<.001	<.001	3	6
LSCC	PPM1F →	+0.270	+0.779	<.001	<.001	3	6
BRCA	PDCD6IP →	+0.310	+0.729	<.001	<.001	3	5
OV	NARS2 →	-0.510	-0.588	.002	.003	2	6
UCEC	CSE1L →	-0.396	-0.504	<.001	<.001	3	5
BRCA	DDX27 →	-0.456	-0.812	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,410 associations by consensus.

FRMD4B vs TOP1 — LUAD

Explore this scatter interactively →