FRMD4B

Across TCGA patient cohorts, FRMD4B mutation is significantly associated with the RNA expression of many other genes, with 5,153 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FRMD4B-associated genes across cancer lineages are LINC02563, RNA5SP401, and LINC02305. Each is linked with FRMD4B in more than 2 cancer types. Because this analysis shows association rather than direction, both FRMD4B-to-partner and partner-to-FRMD4B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC02563 grouped by FRMD4B-low versus FRMD4B-high in LIHC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FRMD4B→partner) and Y-score (partner→FRMD4B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	LINC02563 →	+0.197	+5.758	.006	.003	3	3
SKCM	RNA5SP401 →	+0.137	+3.469	<.001	.003	3	2
SKCM	LINC02305 →	+0.057	+2.765	<.001	.004	3	2
BRCA	CSGALNACT2P2 →	+0.360	+5.175	<.001	.007	3	2
UCEC	RNA5SP411 →	+0.860	+1.442	<.001	.001	3	2
UCEC	RPS29P32 →	+0.272	+1.640	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,153 associations by consensus.

LINC02563 by FRMD4B expression — LIHC

Explore this box plot interactively →