FRG2HP

Across TCGA patient cohorts, FRG2HP RNA expression is significantly associated with the go_rna of many other GO terms, with 6,539 significant associations in total. STAD shows the largest number of these associations.

The most reproducible FRG2HP-associated GO terms across cancer lineages are Regulation of epidermis development, Keratinocyte differentiation, and Ephrin receptor signaling pathway. Each is linked with FRG2HP in more than 7 cancer types. Because this analysis shows association rather than direction, both FRG2HP-to-partner and partner-to-FRG2HP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of epidermis development grouped by FRG2HP-low versus FRG2HP-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FRG2HP→partner) and Y-score (partner→FRG2HP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Regulation of epidermis development →	+0.078	+0.065	<.001	<.001	3	8
ESCA	Keratinocyte differentiation →	+0.072	+0.115	<.001	.002	3	8
STAD	Ephrin receptor signaling pathway →	+0.085	+0.074	<.001	<.001	3	8
STAD	Endosome to lysosome transport →	+0.102	+0.073	<.001	<.001	3	7
STAD	Negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway →	+0.051	+0.058	<.001	<.001	3	7
STAD	Mitochondrial membrane organization →	+0.108	+0.061	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,539 associations by consensus.

Regulation of epidermis development by FRG2HP expression — STAD

Explore this box plot interactively →