FRG2HP

Across TCGA pan-cancer cohorts, FRG2HP RNA is linked to patient survival in 11 of 34 cancer types, making it the most broadly survival-associated FRG2HP data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher FRG2HP RNA is associated with worse overall survival. In most high-consensus cancer types, elevated FRG2HP expression acts as an unfavorable survival marker, although some lineages such as SKCM and LUSC show a favorable association.

ACC, KIRC, and THCA are the cancer types where FRG2HP RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	OS	Tertile	II,III,IV	0.518	0.882	<.001	45	view →
KIRC	DFS	Tertile	All	0.483	0.874	<.001	42	view →
THCA	OS	Quartile	IV	0.858	1.000	.009	29	view →
LAML	DFS	Tertile	All	0.068	0.579	<.001	18	view →
LUAD	DFS	Tertile	IV	0.342	0.893	<.001	18	view →
SKCM	DFS	Tertile	IV	0.943	0.159	.031	9	view →
STAD	DFS	Tertile	IV	0.083	0.379	.001	9	view →
PCPG	OS	Tertile	All	0.804	0.957	.037	9	view →
LUSC	DFS	Tertile	II,III,IV	0.721	0.556	.044	6	view →
UCEC	OS	Tertile	All	0.884	0.928	.037	6	view →
HNSC	OS	Median	IV	0.505	0.718	.030	2	view →

Pink = unfavorable, green = favorable. Showing the 11 strongest of 11 lineages.

FRG2HP–ACC (OS)

Open the ACC breakdown →