FRG2EP

Across TCGA patient cohorts, FRG2EP RNA expression is significantly associated with the protein abundance of many other proteins, with 649 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible FRG2EP-associated proteins across cancer lineages are PPIP5K2_S1108, RFC1_S1090, and RFX1_S159. Each is linked with FRG2EP in more than 1 cancer types. Because this analysis shows association rather than direction, both FRG2EP-to-partner and partner-to-FRG2EP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FRG2EP versus PPIP5K2_S1108 in CCRCC, with a Pearson correlation of -0.23.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FRG2EP→partner) and Y-score (partner→FRG2EP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	PPIP5K2_S1108 →	-0.474	-0.165	<.001	.008	3	1
LSCC	RFC1_S1090 →	+0.344	+0.184	.004	.005	3	1
LSCC	RFX1_S159 →	-0.264	-0.106	.002	.001	3	1
LSCC	SCAMP3_S85 →	+1.233	+0.391	<.001	.008	3	1
LSCC	SDK1_S2113 →	+0.831	+0.488	.009	.002	3	1
LSCC	SEC16A_S2304 →	+0.579	+0.203	.006	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 649 associations by consensus.

FRG2EP vs PPIP5K2_S1108 — CCRCC

Explore this scatter interactively →