Across TCGA patient cohorts, FRG2B mutation is significantly associated with the RNA expression of many other genes, with 94 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible FRG2B-associated genes across cancer lineages are ORC1P1, LINC01789, and VN1R74P. Each is linked with FRG2B in more than 1 cancer types. Because this analysis shows association rather than direction, both FRG2B-to-partner and partner-to-FRG2B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FRG2B→partner) and Y-score (partner→FRG2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ORC1P1 →	+0.061	+4.868	.001	.004	3	2
SKCM	LINC01789 →	+0.055	+4.324	.003	.007	3	2
SKCM	VN1R74P →	+0.077	+4.594	<.001	.008	3	2
COAD	GOLGA6L16P →	+0.029	+7.741	<.001	.009	3	1
COAD	TSPY24P →	+0.159	+7.741	<.001	.009	3	1
COAD	PPP1R26P2 →	+0.009	+7.741	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 94 associations by consensus.

Exploration

FRG2B survival (RNA) · tumor vs normal (RNA) · all FRG2B data types