Across TCGA patient cohorts, FRG2 mutation is significantly associated with the RNA expression of many other genes, with 385 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FRG2-associated genes across cancer lineages are PATL1, GAGE12H, and HSPD1P18. Each is linked with FRG2 in more than 1 cancer types. Because this analysis shows association rather than direction, both FRG2-to-partner and partner-to-FRG2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FRG2→partner) and Y-score (partner→FRG2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PATL1 →	+0.529	+2.364	.003	.003	3	2
LUAD	GAGE12H →	+0.297	+4.748	<.001	.003	3	2
LUAD	HSPD1P18 →	+0.077	+3.480	<.001	.005	3	2
UCEC	TSPY8 →	+0.007	+5.066	<.001	.001	3	2
UCEC	RNA5SP413 →	+0.733	+1.955	.005	.005	3	2
SKCM	CYMP →	+0.034	+3.339	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 385 associations by consensus.

Exploration

FRG2 survival (RNA) · tumor vs normal (RNA) · all FRG2 data types