FRG1BP

Across TCGA pan-cancer cohorts, FRG1BP Mutation is linked to patient survival in 4 of 34 cancer types, making it a survival-associated FRG1BP data layer compared with 19 for mass-spec protein.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher FRG1BP Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated FRG1BP expression acts as an unfavorable survival marker.

COAD, BRCA, and LIHC are the cancer types where FRG1BP Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	OS	Median	All	0.117	0.809	<.001	18	view →
BRCA	OS	Median	All	0.164	0.579	.025	16	view →
LIHC	DFS	Median	All	0.100	0.543	.038	6	view →
SKCM	DFS	Median	III,IV	0.063	0.648	.003	6	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

FRG1BP–COAD (OS)

Open the COAD breakdown →