FRG1-DT

Across TCGA pan-cancer cohorts, FRG1-DT RNA is linked to patient survival in 25 of 34 cancer types, making it the most broadly survival-associated FRG1-DT data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher FRG1-DT RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated FRG1-DT expression acts as an unfavorable survival marker, although some lineages such as UCS and BRCA show a favorable association.

ACC, UCS, and LIHC are the cancer types where FRG1-DT RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	DFS	Tertile	All	0.337	0.700	<.001	84	view →
UCS	OS	Median	II,III,IV	0.595	0.218	.002	66	view →
LIHC	DFS	Median	All	0.453	0.621	<.001	62	view →
BRCA	OS	Median	III,IV	0.891	0.762	.002	42	view →
PAAD	OS	Quartile	All	0.661	0.299	<.001	36	view →
LAML	DFS	Quartile	All	0.615	0.279	.001	24	view →
KICH	OS	Median	II,III,IV	0.852	1.000	.022	23	view →
READ	OS	Tertile	III,IV	0.865	0.606	.004	23	view →
KIRP	DFS	Median	IV	0.034	0.527	<.001	18	view →
OV	DFS	Median	IV	0.406	0.231	.018	16	view →
PCPG	DFS	Quartile	All	0.549	0.895	.010	15	view →
HNSC	DFS	Median	III,IV	0.425	0.230	.003	15	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 25 lineages.

FRG1-DT–ACC (DFS)

Open the ACC breakdown →