FRAT2

Across TCGA patient cohorts, FRAT2 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,608 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible FRAT2-associated proteins across cancer lineages are RNF20, P4HB, and UPF2. Each is linked with FRAT2 in more than 5 cancer types. Because this analysis shows association rather than direction, both FRAT2-to-partner and partner-to-FRAT2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FRAT2 versus RNF20 in LSCC, with a Pearson correlation of 0.57.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FRAT2→partner) and Y-score (partner→FRAT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	RNF20 →	+0.212	+0.668	<.001	<.001	3	6
GBM	P4HB →	-0.375	-0.246	<.001	.005	3	6
BRCA	UPF2 →	+0.258	+0.757	<.001	<.001	3	5
BRCA	WAPL →	+0.287	+0.617	<.001	<.001	3	5
BRCA	SIN3A →	+0.246	+0.651	<.001	<.001	3	5
COAD	EHMT1 →	+0.439	+0.576	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,608 associations by consensus.

FRAT2 vs RNF20 — LSCC

Explore this scatter interactively →