FRAT1

Across TCGA cell cohorts, FRAT1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,376 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible FRAT1-associated GO terms across cancer lineages are Regulation of cytoplasmic mRNA processing body assembly, Branched-chain amino acid metabolic process, and Branched-chain amino acid catabolic process. Each is linked with FRAT1 in more than 11 cancer types. Because this analysis shows association rather than direction, both FRAT1-to-partner and partner-to-FRAT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of cytoplasmic mRNA processing body assembly grouped by FRAT1-low versus FRAT1-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FRAT1→partner) and Y-score (partner→FRAT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Regulation of cytoplasmic mRNA processing body assembly →	+0.113	+0.831	<.001	<.001	3	12
LIVER	Branched-chain amino acid metabolic process →	+0.100	+1.290	<.001	<.001	3	11
LIVER	Branched-chain amino acid catabolic process →	+0.104	+1.290	<.001	<.001	3	10
OESOPHAGUS	Response to aluminum ion →	+0.165	+1.087	.002	<.001	3	10
URINARY_TRACT	Copper ion export →	-0.176	-0.519	<.001	.002	3	10
OESOPHAGUS	Response to mercury ion →	+0.138	+0.616	<.001	.002	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,376 associations by consensus.

Regulation of cytoplasmic mRNA processing body assembly by FRAT1 expression — OESOPHAGUS

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