FRA10AC1

Across TCGA patient cohorts, FRA10AC1 mutation is significantly associated with the RNA expression of many other genes, with 911 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FRA10AC1-associated genes across cancer lineages are RNU7-190P, TRAJ47, and RN7SL429P. Each is linked with FRA10AC1 in more than 1 cancer types. Because this analysis shows association rather than direction, both FRA10AC1-to-partner and partner-to-FRA10AC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU7-190P grouped by FRA10AC1-low versus FRA10AC1-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FRA10AC1→partner) and Y-score (partner→FRA10AC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RNU7-190P →	+0.681	+4.254	<.001	.003	3	2
UCEC	TRAJ47 →	+0.608	+2.405	<.001	<.001	3	2
COAD	RN7SL429P →	+0.750	+4.418	<.001	.008	3	2
SKCM	SNORD116-10 →	+0.297	+5.039	<.001	.003	3	2
UCEC	LINC02012 →	+0.499	+2.708	.003	.003	3	1
UCEC	CWC25 →	+0.437	+3.860	.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 911 associations by consensus.

RNU7-190P by FRA10AC1 expression — SKCM

Explore this box plot interactively →