FRA10AC1

Across TCGA patient cohorts, FRA10AC1 mutation is significantly associated with the total protein of many other genes, with 4 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FRA10AC1-associated genes across cancer lineages are JNK2, ATM, and Chk2. Each is linked with FRA10AC1 in more than 1 cancer types. Because this analysis shows association rather than direction, both FRA10AC1-to-partner and partner-to-FRA10AC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, JNK2 grouped by FRA10AC1-low versus FRA10AC1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FRA10AC1→partner) and Y-score (partner→FRA10AC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	JNK2 →	+0.200	+1.807	.015	.027	3	1
UCEC	ATM →	-0.662	-3.000	<.001	.001	3	1
UCEC	Chk2 →	-0.199	-1.807	.039	.027	3	1
UCEC	Ku80 →	+0.320	+3.013	.001	<.001	2	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

JNK2 by FRA10AC1 expression — UCEC

Explore this box plot interactively →