Across TCGA cell cohorts, FPR3 mutation is significantly associated with the RNA expression of many other genes, with 17 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FPR3-associated genes across cancer lineages are USP29, AUH, and MMP26. Each is linked with FPR3 in more than 1 cancer types. Because this analysis shows association rather than direction, both FPR3-to-partner and partner-to-FPR3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FPR3→partner) and Y-score (partner→FPR3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	USP29 →	+0.033	+4.044	<.001	.003	3	1
LARGE_INTESTINE	AUH →	+0.582	+3.064	.003	.009	3	1
LARGE_INTESTINE	MMP26 →	+0.038	+3.310	<.001	<.001	3	1
LARGE_INTESTINE	GCSAML →	+0.025	+2.648	.001	.008	3	1
LARGE_INTESTINE	SIGLECL1 →	+0.010	+2.977	<.001	.006	3	1
LARGE_INTESTINE	TMEM38A →	+0.675	+3.067	.009	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 17 associations by consensus.

Exploration

FPR3 survival (RNA) · tumor vs normal (RNA) · all FPR3 data types