FOXRED2

Across TCGA cell cohorts, FOXRED2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,866 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible FOXRED2-associated GO terms across cancer lineages are Positive regulation of mitotic cytokinesis, Positive regulation of T-helper 17 cell lineage commitment, and Negative regulation of chromosome condensation. Each is linked with FOXRED2 in more than 14 cancer types. Because this analysis shows association rather than direction, both FOXRED2-to-partner and partner-to-FOXRED2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of mitotic cytokinesis grouped by FOXRED2-low versus FOXRED2-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FOXRED2→partner) and Y-score (partner→FOXRED2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Positive regulation of mitotic cytokinesis →	+0.182	+1.173	<.001	<.001	3	15
STOMACH	Positive regulation of T-helper 17 cell lineage commitment →	+0.206	+1.422	.002	.001	3	15
SOFT_TISSUE	Negative regulation of chromosome condensation →	+0.141	+1.083	<.001	.001	3	15
UPPER_AERODIGESTIVE_TRACT	Mitotic chromosome condensation →	+0.152	+0.965	.003	.005	3	14
UPPER_AERODIGESTIVE_TRACT	Double-strand break repair →	+0.072	+1.184	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	DNA replication-dependent chromatin assembly →	+0.148	+1.477	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,866 associations by consensus.

Positive regulation of mitotic cytokinesis by FOXRED2 expression — PANCREAS

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