FOXRED2

Across TCGA cell cohorts, FOXRED2 mutation is significantly associated with the RNA expression of many other genes, with 252 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FOXRED2-associated genes across cancer lineages are CBY1, OSCP1, and AZIN2. Each is linked with FOXRED2 in more than 1 cancer types. Because this analysis shows association rather than direction, both FOXRED2-to-partner and partner-to-FOXRED2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CBY1 grouped by FOXRED2-low versus FOXRED2-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FOXRED2→partner) and Y-score (partner→FOXRED2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	CBY1 →	+0.540	+3.307	.001	.003	3	2
BLOOD_Leukemia	OSCP1 →	+0.940	+3.176	<.001	.008	3	2
LARGE_INTESTINE	AZIN2 →	+0.784	+2.432	.003	.007	3	2
LARGE_INTESTINE	SLX1B →	+0.757	+2.743	.009	.001	3	2
LARGE_INTESTINE	CYFIP2 →	+1.194	+2.043	.002	.008	3	2
LARGE_INTESTINE	ARHGAP44 →	+1.272	+3.459	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 252 associations by consensus.

CBY1 by FOXRED2 expression — LARGE_INTESTINE

Explore this box plot interactively →