FOXR1

Across TCGA patient cohorts, FOXR1 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,048 significant associations in total. STAD shows the largest number of these associations.

The most reproducible FOXR1-associated GO terms across cancer lineages are mRNA 3'-end processing, Regulation of DNA repair, and Protein-RNA complex organization. Each is linked with FOXR1 in more than 21 cancer types. Because this analysis shows association rather than direction, both FOXR1-to-partner and partner-to-FOXR1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, mRNA 3'-end processing grouped by FOXR1-low versus FOXR1-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FOXR1→partner) and Y-score (partner→FOXR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	mRNA 3'-end processing →	+0.081	+0.173	<.001	<.001	3	22
STAD	Regulation of DNA repair →	+0.061	+0.141	<.001	<.001	3	21
ESCA	Protein-RNA complex organization →	+0.075	+0.157	<.001	<.001	3	20
ESCA	Macromolecule methylation →	+0.065	+0.154	<.001	<.001	3	20
STAD	Positive regulation of DNA repair →	+0.057	+0.156	<.001	<.001	3	20
STAD	Obsolete histone modification →	+0.062	+0.132	<.001	<.001	3	20

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,048 associations by consensus.

mRNA 3'-end processing by FOXR1 expression — ESCA

Explore this box plot interactively →