FOXR1

Across TCGA pan-cancer cohorts, FOXR1 RNA differs between tumor and matched normal tissue in 6 of 18 cancer types tested, making tumor–normal expression one of FOXR1’s most consistent transcriptional readouts.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where FOXR1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types FOXR1 is over-expressed in tumor, although a few such as BRCA and THCA show the opposite, repressed pattern.

BLCA, BRCA, and KIRC are the cancer types where FOXR1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in FOXR1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BLCA	Male	III,IV	+0.088	.004	5	view →
BRCA	All	All	−0.033	.013	4	view →
KIRC	All	All	+0.018	.003	4	view →
LUAD	All	All	+0.051	.025	3	view →
THCA	Male	All	−0.050	.043	1	view →
LIHC	All	All	+0.013	.022	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 6 strongest of 6 lineages.

FOXR1–BLCA

Open the BLCA breakdown →