FOXR1

Across TCGA cell cohorts, FOXR1 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible FOXR1-associated genes across cancer lineages are CFC1B, SPATA31D4, and OR13C3. Each is linked with FOXR1 in more than 1 cancer types. Because this analysis shows association rather than direction, both FOXR1-to-partner and partner-to-FOXR1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CFC1B grouped by FOXR1-low versus FOXR1-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FOXR1→partner) and Y-score (partner→FOXR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	CFC1B →	+0.070	+6.022	<.001	.001	3	1
SKIN	SPATA31D4 →	+0.205	+4.977	<.001	.007	3	1
SKIN	OR13C3 →	+0.030	+6.022	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

CFC1B by FOXR1 expression — SKIN

Explore this box plot interactively →