FOXR1

Across TCGA cell cohorts, FOXR1 mutation is significantly associated with the mutation status of many other genes, with 961 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible FOXR1-associated genes across cancer lineages are GPR162, USPL1, and SEMA4F. Each is linked with FOXR1 in more than 2 cancer types. Because this analysis shows association rather than direction, both FOXR1-to-partner and partner-to-FOXR1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GPR162 grouped by FOXR1-low versus FOXR1-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FOXR1→partner) and Y-score (partner→FOXR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	GPR162 →	+4.321	+5.285	.005	.005	1	3
BLOOD_Leukemia	USPL1 →	+4.000	+5.050	.008	.008	1	2
BLOOD_Leukemia	SEMA4F →	+4.000	+5.050	.008	.008	1	2
BLOOD_Leukemia	FHAD1 →	+4.321	+5.285	.005	.005	1	2
BLOOD_Leukemia	RNF44 →	+4.736	+5.560	.003	.003	1	2
BLOOD_Leukemia	WDR6 →	+4.000	+5.050	.008	.008	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 961 associations by consensus.

GPR162 by FOXR1 expression — BLOOD_Leukemia

Explore this box plot interactively →