FOXP4

Across TCGA patient cohorts, FOXP4 mutation is significantly associated with the RNA expression of many other genes, with 3,327 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FOXP4-associated genes across cancer lineages are RN7SL321P, CICP28, and STMN1P2. Each is linked with FOXP4 in more than 2 cancer types. Because this analysis shows association rather than direction, both FOXP4-to-partner and partner-to-FOXP4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL321P grouped by FOXP4-low versus FOXP4-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FOXP4→partner) and Y-score (partner→FOXP4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	RN7SL321P →	+0.230	+4.760	<.001	.003	3	3
LIHC	CICP28 →	+0.011	+5.108	.005	.008	3	2
READ	STMN1P2 →	+0.118	+5.421	<.001	.005	3	2
READ	RNU6-789P →	+0.713	+5.039	<.001	.008	3	2
SKCM	KIF23 →	+0.727	+3.478	.009	.002	3	2
COAD	MIR6509 →	+0.937	+3.951	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,327 associations by consensus.

RN7SL321P by FOXP4 expression — CESC

Explore this box plot interactively →