FOXP1-IT1

Across TCGA pan-cancer cohorts, FOXP1-IT1 RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated FOXP1-IT1 data layer.

The strongest signal is observed in thyroid carcinoma (THCA), where higher FOXP1-IT1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated FOXP1-IT1 expression acts as an unfavorable survival marker, although some lineages such as UCS and HNSC show a favorable association.

THCA, LUSC, and UCS are the cancer types where FOXP1-IT1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
THCA	OS	Tertile	II,III,IV	0.890	0.990	<.001	82	view →
LUSC	DFS	Median	II,III,IV	0.495	0.693	<.001	72	view →
UCS	DFS	Median	IV	0.952	0.367	.001	62	view →
HNSC	DFS	Median	All	0.753	0.660	.004	36	view →
KICH	OS	Median	III,IV	0.125	0.815	<.001	32	view →
BRCA	DFS	Median	III,IV	0.916	0.835	.006	28	view →
LGG	OS	Median	All	0.939	0.859	.001	24	view →
SKCM	DFS	Median	All	0.702	0.544	<.001	22	view →
OV	OS	Median	IV	0.263	0.481	.010	18	view →
MESO	DFS	Quartile	II,III,IV	0.247	0.429	.025	15	view →
PRAD	OS	Median	All	0.988	1.000	.020	14	view →
KIRC	DFS	Quartile	IV	0.307	0.542	.017	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

FOXP1-IT1–THCA (OS)

Open the THCA breakdown →