FOXP1-IT1

Across TCGA pan-cancer cohorts, FOXP1-IT1 RNA differs between tumor and matched normal tissue in 8 of 18 cancer types tested, making tumor–normal expression one of FOXP1-IT1’s most consistent transcriptional readouts.

The strongest signal is observed in stomach adenocarcinoma (STAD), where FOXP1-IT1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types FOXP1-IT1 is over-expressed in tumor, although a few such as THCA and LUSC show the opposite, repressed pattern.

STAD, HNSC, and THCA are the cancer types where FOXP1-IT1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in FOXP1-IT1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
STAD	All	All	+0.181	.003	4	view →
HNSC	Male	All	+0.022	.007	4	view →
THCA	Female	All	−0.033	<.001	3	view →
PAAD	Male	All	+0.195	.028	2	view →
BRCA	All	All	+0.179	.046	2	view →
CHOL	All	All	+0.051	.006	2	view →
LUSC	Female	III,IV	−0.025	.037	1	view →
KIRC	Male	III,IV	−0.013	.012	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 8 strongest of 8 lineages.

FOXP1-IT1–STAD

Open the STAD breakdown →