FOXP1-AS1

RNA — tumor vs normal
Tumor vs NormalRNABox plot · TCGA cohorts

Across TCGA pan-cancer cohorts, FOXP1-AS1 RNA differs between tumor and matched normal tissue in 7 of 18 cancer types tested, making tumor–normal expression one of FOXP1-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where FOXP1-AS1 RNA is repressed in tumor relative to normal tissue. In most cancer types FOXP1-AS1 is over-expressed in tumor, although a few such as THCA and KIRC show the opposite, repressed pattern.

THCA, KIRC, and LUSC are the cancer types where FOXP1-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in FOXP1-AS1 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.
LineageGenderStageFold-changepSampling consensus
THCAFemaleAll−0.240<.0019view →
KIRCAllAll−0.066<.0016view →
LUSCMaleAll−0.234<.0014view →
PRADAllAll+0.259.0122view →
COADMaleAll+0.180.0252view →
ESCAFemaleAll−0.710.0421view →
KIRPAllAll−0.075.0351view →
Pink = over-expressed in tumor, green = repressed in tumor. Showing the 7 strongest of 7 lineages.

FOXP1-AS1–THCA

Tumor-vs-normal expression box plot for FOXP1-AS1 RNA in THCA.

Open the THCA breakdown →

Exploration